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PRESERVATIVE EFFICACY TESTING

Antimicrobial Preservatives are substances added to Products to protect them from Microbiological Growth or from Microorganisms 1that are introduced inadvertently [that may be introduced inadvertently] during or subsequent to the Manufacturing Process.

2They determine the occurrence of Ingress or Growth [these deter both, i.e. the Ingress and Growth] of Micro-organisms during/ after Manufacture or subsequently, during handling of Multiple-Dose Containers. Microbes can cause the Product to spoil, thus reducing its Shelf-Life, but more importantly, the Potential for Contamination with Potentially Pathogenic Strains, i.e. those that cause Disease and are dangerous to end-users, can greatly increase in the Absence of Preservatives. Cosmetics are well known for their ability to Support Microbial Growth. Water-based Products with a Neutral pH have been shown to be the most Susceptible. In the case of Products Packaged in Multiple- Dose Containers, Antimicrobial Preservatives are added to inhibit the Growth of Micro-Organisms that may be introduced from repeatedly withdrawing 3Individual [Single] Use Doses.

4Efficacy Testing is especially an area that highlights EFRAC’s Expertise. We at EFRAC, perform routine Preservative Efficacy Testing for a wide Range of Cosmetics & Personal Care Products as per different Pharmacopoeias well as clients shared Methods.

[EFRACs Efficacy Tests for Preservatives applicable to a wide Range of Cosmetics & Personal Care Products as per different Pharmacopoeias and, the client shared Methods reflects its Expertise in this field.]

4With the most advanced ICPMS systems we can detect ppm levels of elements like mercury, cadmium, zinc and so on in microseconds. [Advanced ICPMS systems in EFRAC enable the detection of deleterious elements like mercury, cadmium, and zinc at ppm levels in microseconds]

5In order to retain data confidentiality and traceability, EFRAC’s equipment is compatible with LIMS which enables digitized integration of all the instruments through USFDA compliance software connected through a centralized server.

[EFRACs LIMS-compatible equipment enables digitized integration of all the instruments through USFDA-compliant software within a client-server environment thus assuring data confidentiality and traceability.]

Analytical Services .................. Preservative Efficacy Testing